柏哲德氏症是一種不常見的乳腺癌類型,通常最先表現為乳頭的變化。最常見的症狀是乳頭上出現紅色的鱗屑性皮膚疹。這種皮疹可能會蔓延到乳頭周圍較暗的皮膚區域(乳暈)。
柏哲德氏症可能與其他皮膚病症,例如濕疹,外觀相似。但亦有不同之處,舉例而言,柏哲德氏症會影響到乳頭,而乳房上的濕疹通常會影響到乳暈,並且很少影響到乳頭。另外,柏哲德氏症通常僅發生在單側乳房上,而大多數其他皮膚病症則往往會同時影響到雙側乳房。
大多數患有柏哲德氏症的人,在乳頭或乳房其他部位都會有早期乳腺癌的形態表現,即「原位癌(DCIS)」。因此,只要乳頭出現濕疹性變化,通常優先懷疑是柏哲德氏症,並且積極作出正確的鑑別診斷。
#DCIS
Paget’s disease of the breast is an uncommon type of breast cancer that usually first shows as changes to the nipple.
The most common symptom is a red, scaly rash on the nipple. The rash may spread to the darker area of skin around the nipple (areola).
Paget’s disease can look like other skin conditions such as eczema. But there are differences. For example, Paget’s disease affects the nipple while eczema on the breast generally affects the areola and rarely affects the nipple. Also, Paget’s disease usually occurs in one breast while most other skin conditions tend to affect both breasts.
Most people with Paget’s disease will have an early form of breast cancer - known as ductal carcinoma in situ (DCIS) - under the nipple or elsewhere in the breast.
Paget’s disease is highly suggested whenever eczematous changes to the nipple.
#DCIS
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