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Discover the advantages of 3D culture for directed neuronal differentiation of pluripotent stem cells (PSC).
This presentation discusses the advantages of 3D culture for directed neuronal differentiation of pluripotent stem cells (PSC). Researchers have come to the realization that 2D systems do not accurately model the complex cell interactions and self-organizing architecture of the brain. Neuroscientists are increasingly turning to 3D organoid systems that include a greater diversity of cell types and more closely mimic brain development in vivo.
We discuss how we generated organoids rich in functional midbrain dopaminergic (DA) neurons, the specific cells which degenerate in Parkinson’s Disease (PD), while reducing our time and effort.
#ThermoFisher #GibcoCellCulture #PSC #Organoid #3DOrganoid
Негізгі бет Ғылым және технология 3D Organoid Models for Differentiation of PSC-Derived Dopaminergic Neurons
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