messed up my audio a bit here...i just got too excited to talk about this paper
@FunMushizzle
Жыл бұрын
Very interesting. The reason we age is because there has been no evolutionary reason to make a lifeform that lives forever, once we've lived long enough to reproduce that's it as far as our genes are concerned we're done. if we want to live forever we'll have to solve different aging problems in about 300 different tissues in such a way that causes no cancers or serious adverse effects. It's a mammoth task that is seriously underfunded.
@PaulSchwarzer-ou9sw
Жыл бұрын
agree 100%. Aging is imo the root cause of most of our problems.
@williamwalker6071
Жыл бұрын
(?) Nature already gave us the Bowhead Whale that lives 230 years with 500 times our cell number. So it has 1000 times our cancer control. And they're still breaking 15 feet of ice with their back when they're 230... that's not "forever", but it's a hell of a lot better than we do.
@addictedtochocolateandcoff9582
Жыл бұрын
we have 300 different tissues??!!! 😯😯
@larryc1616
Жыл бұрын
We can live forever as an AI generated you 🎉
@MyFirstHandle
Жыл бұрын
@@PaulSchwarzer-ou9sw The biggest reason why people hates singles, widowed, childless, and unmarried peoples as we get older. Time is a curse to all of us because of aging.
@SeanWest-ox6wq
Жыл бұрын
Fantastic summary of the paper, as you always manage to do! I wonder if the fast moving AI developments could somehow aid in analyzing the potential oscillating elements of these gene circuits within mammalian cells...
@KenOtwell
Жыл бұрын
"Could be something very well worth pursuing".... understatement of the year!
@TheSheekeyScienceShow
Жыл бұрын
Haha, yeah that's my Britishness summarised
@stevebelzer4758
Жыл бұрын
LOVEyour diagrams and little animated cutaways - With the exponential advances of longevity science , at age 69 I’m hopeful a “epigenetic reset “ will will be developed using Yamanaka factors etc - it will in your lifetime . Just be sure your money lasts as long as you do
@MyFirstHandle
Жыл бұрын
We can live longer like those of immortal jellyfish. They do not question their purpose as they are only there to live their lives in peace for a very long time. I like to be one of them and nothing to worry about getting old or any sort of marital status whatsoever.
@mpen7873
Жыл бұрын
Most excellent, videos and papers like this provide positive motivation for the long term success of genetics to help humans 😄
@FoZeusMaximus
Жыл бұрын
Thank you, that was very informative.
@GeoffryGifari
Жыл бұрын
if there is already a long-lived mutated strain of yeast which chooses either pathway, maybe gene oscillation applied to the mutants would make it live even longer?
@Zerpentsa6598
Жыл бұрын
You may live longer, but in your old age you'll be indecisive and frightened of commitment.
@jesseshaver2262
Жыл бұрын
What are your thoughts on cyclodextrin? Some have injected it themselves and stated it can remove both soft and hardened plaque in the arteries…… that seems to be what the animal studies show too. Is this too good to be true, do you think we can actually “clean” our arteries with it?
@SilverFan21k
Жыл бұрын
Subscribed. 🙂
@curingaging
Жыл бұрын
Great video! I only recently learned about the exciting work from Nan Hao's lab.
@SlamminGraham
Жыл бұрын
Absolutely fascinating!!!
@seabeepirate
Жыл бұрын
Notes on the post human transition - lifespans are growing through technology. As environmental pressures like population density, access to resources and environmental pollution direct our biology will future people be resilient enough to endure change?
@aevitas8386
Жыл бұрын
So how can this be integrated with what has been said so far about hyperactivation of Sir2 increasing longevity? Is it that mitochondrial dysfunction is less damaging than the loss of gene silencing, so if instead of oscillating you push the system that way you still get a benefit above normal metabolism?
@themacso4157
Жыл бұрын
My cat is 1year old and i love her. Will these breakthroughs come soom enough so she may live twice as much??
@GeoffryGifari
Жыл бұрын
hmm even though the two genes switch between each other, their expressions still accumulate right? so aging will be slowed down but not stopped
@medicinefuture
Жыл бұрын
thanks so much
@GeoffryGifari
Жыл бұрын
And why would a species like yeast have two aging pathways? is this common?
@aljosarojac8575
Жыл бұрын
Great presentation. Fantastic. Could you find out from those people, how the length of the cycle (the frequency of the switch) affects the life extension?
@TheSheekeyScienceShow
Жыл бұрын
That's a really good question. I should also reach out to the group
@DeeneMuada
Жыл бұрын
have you heard of methyleneblue beeing a electron carrier?
@kingsize1182
Жыл бұрын
💯🔥👍
@SpringChickensOnlyMan
Жыл бұрын
I am saving money for my brain to be cut out in 2030 so I can become a robot.
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