Jennifer Lippincott-Schwartz's research uses live cell imaging approaches to analyze the spatio-temporal behavior and dynamic interactions of molecules and organelles in cells. Her group has pioneered the use of green fluorescent protein (GFP) technology for quantitative analysis and modeling of intracellular protein traffic and organelle biogenesis in live cells and embryos, providing novel insights into cell compartmentalization, protein trafficking and organelle inheritance. Most recently, her research has focused on the development and use of photoactivatable fluorescent proteins, which ‘switch on’ in response to light. One application of these proteins she has put to use is photoactivated localization microscopy, (i.e., PALM), a superresolution imaging technique that enables visualization of molecule distributions at high density at the nano-scale.
Jennifer Lippincott-Schwartz is widely recognized for her numerous research achievements.
Негізгі бет Ғылым және технология Eukaryotic cell compartmentalization: Insights from imaging (Jennifer Lippincott-Schwartz)
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