Given the strong evidence for the role of the microbiome in autoimmune diseases, fecal transplant from a donor has been proposed as a potential treatment of MS. This video looks at the theory behind fecal microbiota transplant and the published data in MS.
Selected sources:
Fecal microbiota transplantation associated with 10 years of stability in a patient with SPMS: www.ncbi.nlm.nih.gov/pmc/arti...
Fecal Microbiota Transplantation (FMT) in Multiple Sclerosis (MS) [2 case reports]: journals.lww.com/ajg/fulltext...
FMT in EAE: www.ncbi.nlm.nih.gov/pmc/arti...
Dr. Jeffrey Gelfand’s FMT study: clinicaltrials.gov/ct2/show/N...
Review of FMT in MS: journals.sagepub.com/doi/full...
Actrims presentation of FMT on MS: multiplesclerosisnewstoday.co...
FMT In neurological diseases review: www.frontiersin.org/articles/...
Single-Arm, Non-randomized, Time Series, Single-Subject Study of Fecal Microbiota Transplantation in Multiple Sclerosis: www.frontiersin.org/articles/...
Daily, oral FMT for long-term maintenance therapy in ulcerative colitis: results of a single-center, prospective, randomized pilot study: pubmed.ncbi.nlm.nih.gov/34238...
Influence of a High-Impact Multidimensional Rehabilitation Program on the Gut Microbiota of Patients with Multiple Sclerosis: www.mdpi.com/1422-0067/22/13/...
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Dr. Brandon Beaber is a board-certified neurologist with subspecialty training in multiple sclerosis and other immunological diseases of the nervous system. He is a partner in the Southern California Permanente Medical Group and practices in Downey, California (South Los Angeles). He has several publications on MS epidemiology and has participated in clinical trials for MS therapeutics. You can follow him on twitter @Brandon_Beaber where he regularly posts about MS news and research.
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he video material by Dr. Brandon Beaber is general educational material on health conditions and is not intended to be used by viewers to diagnose or treat any individual's medical condition. Specifically, this material is not a substitute for individualized diagnostic and treatment advice by a qualified medical/health practitioner, licensed in your jurisdiction, who has access to the relevant information available from diagnostic testing, medical interviews, and a physical examination. To the extent that Dr. Beaber endorses any lifestyle change, behavioral intervention, or supplements, the viewer should consult with a qualified healthcare professional to determine the safety and efficacy of the intervention in light of their individualized information.
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