We worry about insulin resistance because it's linked to the metabolic syndrome. the metabolic syndrome is a constellation of
• high blood glucose
• high blood pressures
• abdominal obesity
• high triglycerides
• Low HDL
and that together really raises the risk of other diseases such as
• heart attacks
• strokes
• cancer
• Alzheimer
• PCOS
• Migraine
• Skin Tags
• Large patches of darker skin
• Acne
• Bone Health
• Kidney issue
• Nerve damage
so because it's such a big risk factor. we need to know what is insulin resistance and how we can treat it.
Insulin resistance : we have glucose, cells and the insulin receptor. insulin is a hormone that is naturally produced by the pancreas and it's produced in response to feeding.
so in the normal situation as we start to eat and the glucose starts to go up and the insulin then attaches to the insulin receptor which is on the cell surface and this is going to open up the doorway so that glucose now can enter the cell and the cell needs this as a source of energy.
so when the insulin is high the receptor opens it like a gate and in goes the glucose. once it's done then the body has a source of energy. Glucose is removed from the blood at that point the glucose might be used by the cell for immediate energy needs or stored as glycogen for later energy needs when it gets to fasting when you're not eating then the insulin levels go down and that's the signal that your body is going to start to use stored energy now.
just remember everyone insulin controls the fuel the body uses, what type of fuel it uses, how much it's using it.
whether it wants to store some of the energy or nutrients or or burn them and how they're burned. typically the body uses combinations of glucose and fat for energy needs. but for some people particularly those who are overweight and possibly pre-diabetic a condition referred to as insulin resistance occurs. for the glucose what this can mean is that insulin has become inefficient at telling cells to open the door to let the glucose in. glucose levels stay elevated in the blood. now this could be due to the lack of insulin like in type 1 diabetes. but in this situation we can measure the insulin and the insulin levels are normal on high side. the pancreas senses this and it makes more insulin at least initially the extra insulin will then be enough to convince the cells to let glucose in. but as the situation continues it may require more and more and more insulin to get the same amount of glucose into the cells. glucose concentrations in the blood may look normal but this comes as a result of having elevated insulin in the blood and that insulin has other effects. when we talk about insulin resistance what we see is that there is a large amount of insulin outside in the bloodstream more than usual.
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