QIMR Berghofer researchers have conducted the first comprehensive two-year laboratory characterisation of the rare sub-type of the mosquito-borne Japanese Encephalitis Virus (JEV) that caused an unprecedented deadly outbreak in Australia in 2022.
The study, which was conducted in QIMR Berghofer’s cutting-edge high biocontainment facility, showed the strain’s potential to cause fatal brain infection and establishes technologies to test new vaccines to protect Australian populations.
QIMR Berghofer’s senior research officer Dr Daniel Rawle and research officer Dr Wilson Nguyen found the new virus strain’s impact on the brain is consistent with the 7 human fatalities during the unprecedented 2022 outbreak, which involved 44 confirmed human cases across Victoria, New South Wales, South Australia, Northern Territory and Queensland.
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