PREVENT NAD+ LEVELS FROM DECLINING BY INHIBITING CD38. More than anything else, CD38 exhausts the supply of NAD+ in our bodies.
I've talked a lot about how NAD+ levels decline with age, and how you can restorer reduced NAD+ to youthful levels by supplementing with NAD+ precursors, like NMN and NR. But what if you could prevent NAD+ levels from decreasing in the first place? You can, by inhibiting the activity of CD38.
In today's video, we'll be covering what CD38 is and how it impacts aging by using up our supply of NAD+...more than any other molecule. We'll then move into a discussion of how supplementing with apigenin and quercetin and help to inhibit the activity of CD38 and maintain NAD+ levels as we age.
Links to studies in this video:
CD38 Is A NADase: The Pharmacology of CD38/NADase: An emerging target for cancer and aging diseases / www.ncbi.nlm.nih.gov/pmc/arti...
As CD38 Levels Rise, NAD+ Levels Decline: CD38 dictates age-related NAD decline and mitochondrial dysfunction through a SIRT3-dependent mechanism / www.ncbi.nlm.nih.gov/pmc/arti...
Apigenin & Quercetin Inhibit CD38: Flavonoid Apigenin Is an Inhibitor of the NAD+ase CD38 / www.ncbi.nlm.nih.gov/pmc/arti...
Quercitin Phytosome Is More Bioavailable: Improved Oral Absorption of Quercetin from Quercetin Phytosome®, a New Delivery System Based on Food Grade Lecithin / pubmed.ncbi.nlm.nih.gov/30328...
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Негізгі бет Ғылым және технология RAISE NAD+ WITH APIGENIN & QUERCETIN: Reduce CD38 To Boost NAD+ Levels [2021]
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