Because host cells have no enzyme that can replicate viral RNA or make mRNA, the genomes of RNA viruses must encode an RNA polymerase. In this lecture we discuss the principles and mechanisms of RNA synthesis by RNA dependent RNA polymerases, including priming of RNA synthesis, how mRNA and genomes are produced in infected cells, and the switch from synthesis of mRNAs to genomes. Out subjects are negative strand RNA viruses, positive strand RNA viruses, and double-stranded RNA viruses.
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Негізгі бет Virology Lectures 2023 #6: Synthesis of RNA from RNA
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