Take these time stamps with a grain of salt. Our conversation bounces around.
00:00 Intro - the genesis of Coffee Break
00:01:00 Global connectivity and systemic LFOs get stronger the longer a subject is in the scanner!
00:38:06 Use of dynamic global signal regression (dGSR) for removal of lag-optimized sLFOs in "de-noising" of fMRI data.
00:53:11 Modulating physiological parameters intentionally.
00:59:35 Phase versus magnitude reconstructions in relation to breathing artifacts.
01:04:30 7 T versus other field strengths, and using clinical hardware & software for neuro research.
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Blaise bio: www.mcleanhospital.org/profil...
Rapidtide github: github.com/bbfrederick/rapidtide
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Here's a blog post I wrote on the origins of systemic low frequency oscillations (sLFOs). If sLFO is a term is new to you, I'd suggest at least quickly perusing this blog to give you a grounding before you watch Blaise and me chat.
practicalfmri.blogspot.com/20...
I did a brief intro to Rapidtide as part of my talk at the 2021 Finding Hemo conference. Watch from 1 hr 10 min 02 sec.
• Noise as Signal: Findi...
Blaise also did an intro to sLFOs as part of the same conference. Watch from 1 hr 28 min 36 sec.
• Noise as Signal: Findi...
In this ICP Network talk, Blaise discusses the increasing sLFOs and connectivity he observes in long runs and concatenated fMRI runs.
• Using resting state fM...
And this is the preprint paper on the increasing connectivity/sLFO effect:
www.biorxiv.org/content/10.11...
More on Mayer waves from Wikipedia:
en.wikipedia.org/wiki/Mayer_w...
Taylor Bolt's study on arousal:
www.biorxiv.org/content/10.11...
HAPPY:
Aslan S, Hocke L, Schwarz N, Frederick B. Extraction of the cardiac waveform from simultaneous multislice fMRI data using slice sorted averaging and a deep learning reconstruction filter. Neuroimage. 2019 Sep;198:303-316. doi: 10.1016/j.neuroimage.2019.05.049. Epub 2019 May 23. PMID: 31129302; PMCID: PMC6592732.
(Happy is available as part of the Rapidtide suite, github link above.)
Dynamic global signal regression (dGSR):
Correcting for Blood Arrival Time in Global Mean Regression Enhances Functional Connectivity Analysis of Resting State fMRI-BOLD Signals
www.frontiersin.org/articles/...
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What is Coffee Break?
We all know the best science at a conference happens either during the coffee breaks or in the pub afterwards. This being the case, practiCal fMRI and a guest sit down for coffee (or something stronger) to discuss some aspect of functional neuroimaging in what we hope is an illuminating, honest fashion. It's not a formal presentation. It's not even vaguely polished. It’s simply a frank, open discussion like you might overhear during a conference coffee break.
Disclaimer 1: You are eavesdropping on a conversation between two scientists. There may be colorful language, slang, acronyms and technical jargon. Sorry. There may also be rather poor audio-visual quality. Too bad, suck it up. You're eavesdropping, remember?
Disclaimer 2: No guarantees I'll read or respond to comments. Hopefully you will be able to figure out the acronyms and technical jargon using Google, or else post a question here and hope someone comes to your rescue. Comments about A-V quality? See the first disclaimer.
Негізгі бет Coffee Break! Blaise Frederick discusses systemic low frequency oscillations (sLFOs) in fMRI data.
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